Doxorubicin‐loaded nanoparticle coated with endothelial cells‐derived exosomes for immunogenic chemotherapy of glioblastoma

• Main Authors: Chao Zhang (Author), Jian Song (Author), Lei Lou (Author), Xuejiao Qi (Author), Lei Zhao (Author), Bo Fan (Author), Guozhu Sun (Author), Zhongqiang Lv (Author), Zhenzeng Fan (Author), Baohua Jiao (Author), Jiankai Yang (Author)
• Format: Book
• Published: Wiley, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Treatments of glioblastoma (GBM) have not been very effective, largely due to the inefficiency of drugs in penetrating the blood brain barrier (BBB). In this study, we investigated the potential of exosome‐coated doxorubicin (DOX)‐loaded nanoparticles (ENPDOX) in BBB penetration, inducing i...