High detection rate for disease-causing variants in a cohort of 30 Iranian pediatric steroid resistant nephrotic syndrome cases

• Main Authors: Maryam Najafi (Author), Korbinian M. Riedhammer (Author), Aboulfazl Rad (Author), Paria Najarzadeh Torbati (Author), Riccardo Berutti (Author), Isabel Schüle (Author), Sophie Schroda (Author), Thomas Meitinger (Author), Jasmina Ćomić (Author), Simin Sadeghi Bojd (Author), Tayebeh Baranzehi (Author), Azadeh Shojaei (Author), Anoush Azarfar (Author), Mahmood Reza Khazaei (Author), Anna Köttgen (Author), Rolf Backofen (Author), Ehsan Ghayoor Karimiani (Author), Julia Hoefele (Author), Miriam Schmidts (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundSteroid resistant nephrotic syndrome (SRNS) represents a significant renal disease burden in childhood and adolescence. In contrast to steroid sensitive nephrotic syndrome (SSNS), renal outcomes are significantly poorer in SRNS. Over the past decade, extensive genetic heterogeneity has bec...