Pitfalls and solutions of the fully-automated radiosynthesis of [11C]metoclopramide

• Glavni autori: Verena Pichler (Autor), Marius Ozenil (Autor), Karsten Bamminger (Autor), Chrysoula Vraka (Autor), Marcus Hacker (Autor), Oliver Langer (Autor), Wolfgang Wadsak (Autor)
• Format: Knjiga
• Izdano: SpringerOpen, 2019-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background [11C]Metoclopramide is a new radiotracer for investigating the activity of P-glycoprotein at the blood-brain barrier. A highly stable and reproducible radiosynthesis is a prerequisite for clinical studies applying [11C]metoclopramide or other 11C-labelled radiotracers, therefore...