Screening Naturally Occurring Phenolic Antioxidants for Their Suitability as Additives to CHO Cell Culture Media Used to Produce Monoclonal Antibodies

• मुख्य लेखकों: Luis Toronjo-Urquiza (लेखक), David C. James (लेखक), Tibor Nagy (लेखक), Robert J. Falconer (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2019-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

This study identified several antioxidants that could be used in Chinese hamster ovary (CHO)cell culture media and benefit monoclonal antibody production. The flavan-3-ols, catechin, epicatechin, epigallocatechin gallate and gallocatechin gallate all had no detrimental effect on cell viability at th...