Chrysin Protects Against Titanium Particle-Induced Osteolysis by Attenuating Osteoclast Formation and Function by Inhibiting NF-κB and MAPK Signaling

• Main Authors: Zuoxing Wu (Author), Chen Li (Author), Yu Chen (Author), Qian Liu (Author), Na Li (Author), Xuemei He (Author), Weibin Li (Author), Rong Shen (Author), Li Li (Author), Chenming Wei (Author), Siyuan Shao (Author), Fangsheng Fu (Author), Jiaxin Ding (Author), Xiaochen Sun (Author), Dairong Wang (Author), Guixin Yuan (Author), Yiji Su (Author), Jinmin Zhao (Author), Jiake Xu (Author), Ren Xu (Author), Xin Xu (Author), Feng Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone homeostasis only exists when the physical function of osteoblast and osteoclast stays in the balance between bone formation and resorption. Bone resorption occurs when the two processes are uncoupled, shifting the balance in favour of bone resorption. Excessive activation of osteoclasts leads t...