Whole-exome sequencing of oral epithelial dysplasia samples reveals an association with new genes

• Main Authors: Daniela ADORNO-FARIAS (Author), Jean Nunes dos SANTOS (Author), Wilfredo GONZÁLEZ-ARRIAGADA (Author), Sandra TARQUINIO (Author), Rodrigo Alberto SANTIBÁÑEZ PALOMINOS (Author), Alberto Jesus MARTÍN MARTÍN (Author), Ricardo FERNANDEZ-RAMIRES (Author)
• Format: Knjiga
• Izdano: Sociedade Brasileira de Pesquisa Odontológica, 2023-02-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract The genetic basis of oral epithelial (OED) is unknown, and there is no reliable method for evaluating the risk of malignant transformation. Somatic mutations are responsible for the transformation of dysplastic mucosa to invasive cancer. In addition, these genomic variations could represent...