Sterically stabilized recombined HDL composed of modified apolipoprotein A-I for efficient targeting toward glioma cells

• Main Authors: Jin Li (Author), Mengmeng Han (Author), Jianfei Li (Author), Zhiming Ge (Author), Qianqian Wang (Author), Kai Zhou (Author), Xiaoxing Yin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reconstituted high density lipoprotein (rHDL) has been regarded as a promising brain-targeting vehicle for anti-glioma drugs under the mediation of apolipoprotein A-I (apoA-I). However, some stability issues relating to drug leakage and consequent reduced targeting efficiency in the course of discoi...