Pharmacometabolomics of trabectedin in metastatic soft tissue sarcoma patients

• Main Authors: Giuseppe Corona (Author), Emanuela Di Gregorio (Author), Angela Buonadonna (Author), Davide Lombardi (Author), Simona Scalone (Author), Agostino Steffan (Author), Gianmaria Miolo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Trabectedin is an anti-cancer drug commonly used for the treatment of patients with metastatic soft tissue sarcoma (mSTS). Despite its recognized efficacy, significant variability in pharmacological response has been observed among mSTS patients. To address this issue, this pharmacometabo...