Bilayer Dissolving Microneedles Incorporating Hypericin-Loaded Nanocapsules For Improved Localised Photodynamic Therapy

• Main Authors: Heba M. Abd- (Author), Ismaiel Tekko (Author), Alyaa Ramadan (Author), Noha Nafee (Author), Nawal Khalafallah (Author), Ryan F Donnelly (Author)
• Format: Book
• Published: University of Huddersfield Press, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypericin (Hy) is a potent lipid-soluble photosensitizer having broad pharmacological spectrum. Nevertheless, its poor water solubility leads to its aggregation in the biological systems that consequently diminishes its photodynamic activity (PDA) and its therapeutic applications. Therefore, this st...