The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats

• मुख्य लेखकों: Ping Ma (लेखक), Ning Huang (लेखक), Jun Tang (लेखक), Zunjie Zhou (लेखक), Jing Xu (लेखक), Yi Chen (लेखक), Maoxin Zhang (लेखक), Qin Huang (लेखक), Yuan Cheng (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cerebral edema (CE) exerts an important effect on brain injury after traumatic brain injury (TBI). Upregulation of transient receptor potential melastatin 4 (TRPM4) in vascular endothelial cells (ECs) results in damage to capillaries and the blood-brain barrier (BBB), which is critical for the devel...