A novel S1P1 modulator IMMH002 ameliorates psoriasis in multiple animal models

• Main Authors: Jing Jin (Author), Nina Xue (Author), Yuan Liu (Author), Rong Fu (Author), Mingjin Wang (Author), Ming Ji (Author), Fangfang Lai (Author), Jinping Hu (Author), Xiaojian Wang (Author), Qiong Xiao (Author), Xiaoying Zhang (Author), Dali Yin (Author), Liping Bai (Author), Xiaoguang Chen (Author), Shuan Rao (Author)
• Format: Book
• Published: Elsevier, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Psoriasis is characterized by abnormal proliferation of keratinocytes, as well as infiltration of immune cells into the dermis and epidermis, causing itchy, scaly and erythematous plaques of skin. The understanding of this chronic inflammatory skin disease remains unclear and all available treatment...