Joint modeling of tumor dynamics and progression‐free survival in advanced breast cancer: Leveraging data from amcenestrant early phase I-II trials
Abstract A joint modeling framework was developed using data from 75 patients of early amcenestrant phase I-II AMEERA‐1‐2 dose escalation and expansion cohorts. A semi‐mechanistic tumor growth inhibition (TGI) model was developed. It accounts for the dynamics of sensitive and resistant tumor cells,...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
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Wiley,
2024-06-01T00:00:00Z.
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