A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers

• Үндсэн зохиолчид: Cécile L. Berends (Зохиогч), Lisa Pagan (Зохиогч), Michiel J. vanEsdonk (Зохиогч), Naomi B. Klarenbeek (Зохиогч), Kirsten R. Bergmann (Зохиогч), Matthijs Moerland (Зохиогч), Vincent van derWel (Зохиогч), Saco J. deVisser (Зохиогч), Hans Büller (Зохиогч), Frans deLoos (Зохиогч), Wouter S. deVries (Зохиогч), Hans Waals (Зохиогч), Leo G. J. deLeede (Зохиогч), Jacobus Burggraaf (Зохиогч), Ingrid M. C. Kamerling (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Wiley, 2021-04-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract The strict intake regimen of cysteamine bitartrate formulations, associated with side effects, is a concern for the treatment compliance in cystinosis therapy. Therefore, there is a need for a cysteamine formulation with an improved pharmacokinetic profile. This study investigated the pharm...