Characterization of pharmacogenomic variants in a Brazilian admixed cohort of elderly individuals based on whole-genome sequencing data

• मुख्य लेखकों: Luciana Bertholim-Nasciben (लेखक), Marilia O. Scliar (लेखक), Guilherme Debortoli (लेखक), Bhooma Thiruvahindrapuram (लेखक), Stephen W. Scherer (लेखक), Yeda A. O. Duarte (लेखक), Mayana Zatz (लेखक), Guilherme Suarez-Kurtz (लेखक), Esteban J. Parra (लेखक), Michel S. Naslavsky (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Research in the field of pharmacogenomics (PGx) aims to identify genetic variants that modulate response to drugs, through alterations in their pharmacokinetics (PK) or pharmacodynamics (PD). The distribution of PGx variants differs considerably among populations, and whole-genome sequ...