Inhibition of bacterial and human zinc-metalloproteases by bisphosphonate- and catechol-containing compounds
Compounds containg catechol or bisphosphonate were tested as inhibitors of the zinc metalloproteases, thermolysin (TLN), pseudolysin (PLN) and aureolysin (ALN) which are bacterial virulence factors, and the human matrix metalloproteases MMP-9 and −14. Inhibition of virulence is a putative strategy i...
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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