Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug-drug interaction studies

Abstract N‐Nitrosamine (NA) impurities are considered genotoxic and have gained attention due to the recall of several marketed drug products associated with higher‐than‐permitted limits of these impurities. Rifampicin is an index inducer of multiple cytochrome P450s (CYPs) including CYP2B6, 2C8, 2C...

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Main Authors: Jayaprakasam Bolleddula (Author), Sathej Gopalakrishnan (Author), Ping Hu (Author), Jennifer Dong (Author), Karthik Venkatakrishnan (Author)
Format: Book
Published: Wiley, 2022-09-01T00:00:00Z.
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