RAGE-aptamer Attenuates the Growth and Liver Metastasis of Malignant Melanoma in Nude Mice

• Main Authors: Nobutaka Nakamara (Author), Takanori Matsui (Author), Yuji Ishibashi (Author), Ami Sotokawauchi (Author), Kei Fukami (Author), Yuichiro Higashimoto (Author), Sho-ichi Yamagishi (Author)
• Format: Book
• Published: BMC, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Epidemiological studies have suggested a link between cumulative diabetic exposure and cancer. The interaction of advanced glycation end products (AGEs) with their receptor (RAGE) may contribute to the phenomenon. We examined the effects of DNA aptamer raised against RAGE (RAGE-aptamer) on...