Single Application of A2 NTX, a Botulinum Toxin A2 Subunit, Prevents Chronic Pain Over Long Periods in Both Diabetic and Spinal Cord Injury-Induced Neuropathic Pain Models

• Main Authors: Lin Ma (Author), Jun Nagai (Author), Yuki Sekino (Author), Yoshitaka Goto (Author), Shinji Nakahira (Author), Hiroshi Ueda (Author)
• Formato: Livro
• Publicado em: Elsevier, 2012-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Botulinum toxin type A is a unique candidate for inhibition of pain transmission. In the present study we attempted to see the beneficial actions of A2 neurotoxin (NTX), an active subunit of botulinum toxin type A. Intraplantar injection of A2 NTX significantly suppressed mechanical allodynia and hy...