Cationic Perylene Antivirals with Aqueous Solubility for Studies In Vivo

• Hlavní autoři: Anna A. Shtro (Autor), Anzhelika V. Garshinina (Autor), Vera A. Alferova (Autor), Polina N. Kamzeeva (Autor), Viktor P. Volok (Autor), Ekaterina S. Kolpakova (Autor), Timofei D. Nikitin (Autor), Alexey A. Chistov (Autor), Evgeny S. Belyaev (Autor), Vladimir A. Korshun (Autor), Liubov I. Kozlovskaya (Autor), Andrey V. Aralov (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2022-09-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Perylene-based compounds are attracting significant attention due to their high broad-spectrum antiviral activity against enveloped viruses. Despite unambiguous results of in vitro studies and high selectivity index, the poor water solubility of these compounds prevented in vivo evaluation of their...