Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway

Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway

Background: Endoplasmic reticulum stress (ER stress) plays a critical role in the pathogenesis of liver fibrosis; thus, it can be a potential therapeutic target of fibrosis. However, the mechanism of ER stress regulation in fibrosis, particularly through sirtuin 1 (SIRT1), remains unclear. The objec...

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Main Authors: Jie Zhu (Author), Ruiwen Wang (Author), Ting Xu (Author), Shuai Zhang (Author), Yan Zhao (Author), Zhenlu Li (Author), Chao Wang (Author), Junjun Zhou (Author), Dongyan Gao (Author), Yan Hu (Author), Xiaofeng Tian (Author), Jihong Yao (Author)
Format: Book
Published: Frontiers Media S.A., 2018-11-01T00:00:00Z.
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