The Effect of Thermal-Treating on Drug Release from Sustained Release Alginate-Eudragit RS Matrices

• Principais autores: Ehsan Kaffash (Autor), Mohammadreza Abbaspour (Autor), Hadi Afrasiabi Garekani (Autor), Zohreh Jahanian (Autor), Farinaz Saremnejad (Autor), Abbas Akhgari (Autor)
• Formato: Livro
• Publicado em: Tabriz University of Medical Sciences, 2021-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purpose: The main objective of the present study was to develop the colonic delivery system for 5-aminosalicylic acid (5-ASA) as an anti-inflammatory drug. Methods: Matrix pellets containing various proportions of alginate, calcium and Eudragit® RS were prepared by extrusion-spheronization technique...