The Effect of Thermal-Treating on Drug Release from Sustained Release Alginate-Eudragit RS Matrices

• Main Authors: Ehsan Kaffash (Author), Mohammadreza Abbaspour (Author), Hadi Afrasiabi Garekani (Author), Zohreh Jahanian (Author), Farinaz Saremnejad (Author), Abbas Akhgari (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The main objective of the present study was to develop the colonic delivery system for 5-aminosalicylic acid (5-ASA) as an anti-inflammatory drug. Methods: Matrix pellets containing various proportions of alginate, calcium and Eudragit® RS were prepared by extrusion-spheronization technique...