Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction

• मुख्य लेखकों: Veronica Marcos (लेखक), Zhe Zhou-Suckow (लेखक), Ali Önder Yildirim (लेखक), Alexander Bohla (लेखक), Andreas Hector (लेखक), Ljubomir Vitkov (लेखक), Wolf Dietrich Krautgartner (लेखक), Walter Stoiber (लेखक), Matthias Griese (लेखक), Oliver Eickelberg (लेखक), Marcus A. Mall (लेखक), Dominik Hartl (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2015-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Chronic obstructive lung disease determines morbidity and mortality of patients with cystic fibrosis (CF). CF airways are characterized by a nonresolving neutrophilic inflammation. After pathogen contact or prolonged activation, neutrophils release DNA fibres decorated with antimicrobial proteins, f...