Serum klotho concentrations inversely correlate with the severity of nailfold capillaroscopic patterns in patients with systemic sclerosis

• Main Authors: R. Talotta (Author), F. Rigamonti (Author), T. Letizia (Author), S. Bongiovanni (Author), M.C. Ditto (Author), M. Antivalle (Author), S. Santandrea (Author), F. Atzeni (Author), T. Vago (Author), P. Sarzi-Puttini (Author)
• Format: Book
• Published: PAGEPress Publications, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Klotho is a transmembrane and soluble glycoprotein that governs vascular integrity. Previous studies have demonstrated reduced serum klotho concentrations in patients with systemic sclerosis (SSc), and it is known that klotho deficiency can impair the healing of digital ulcers related to microvessel...