Mucocutaneous Ulcerations and Pancytopenia due to Methotrexate Overdose

• Main Authors: Katharina Knoll (Author), Florian Anzengruber (Author), Antonio Cozzio (Author), Lars E. French (Author), Carla Murer (Author), Alexander A. Navarini (Author)
• Format: Book
• Published: Karger Publishers, 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Methotrexate (MTX) is an antifolic drug used in the treatment of immune-mediated and neoplastic diseases. Initiation or dosage changes in MTX therapy can cause mucositis and bone marrow suppression. Skin lesions due to acute MTX toxicity are rare, but they serve as a herald for later-onset pancytope...