Seed-mediated RNA interference of androgen signaling and survival networks induces cell death in prostate cancer cells

Resistance to anti-androgen therapy in prostate cancer (PCa) is often driven by genetic and epigenetic aberrations in the androgen receptor (AR) and coregulators that maintain androgen signaling activity. We show that specific small RNAs downregulate expression of multiple essential and androgen rec...

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Bibliographic Details
Main Authors: Joshua M. Corbin (Author), Constantin Georgescu (Author), Jonathan D. Wren (Author), Chao Xu (Author), Adam S. Asch (Author), Maria J. Ruiz-Echevarría (Author)
Format: Book
Published: Elsevier, 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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