Acute Hypoxic Stress Affects Migration Machinery of Tissue O2-Adapted Adipose Stromal Cells

• Main Authors: Olga O. Udartseva (Author), Margarita V. Lobanova (Author), Elena R. Andreeva (Author), Sergey V. Buravkov (Author), Irina V. Ogneva (Author), Ludmila B. Buravkova (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ability of mesenchymal stromal (stem) cells (MSCs) to be mobilised from their local depot towards sites of injury and to participate in tissue repair makes these cells promising candidates for cell therapy. Physiological O2 tension in an MSC niche in vivo is about 4-7%. However, most in vitro st...