Melatonin in the prevention of cisplatin-induced acute nephrotoxicity: a randomized, controlled clinical trial

• Main Authors: Sara Karvan (Author), Alireza Sadeghi (Author), Pegah Farrokhi (Author), Amirabbass Nekouee (Author), Mehran Sharifi (Author), Azadeh Moghaddas (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: Cisplatin-induced nephrotoxicity (CisIN) remains the most dose-limiting adverse effect of its clinical use. The protective effects of melatonin on CisIN have been addressed in several non- clinical and animal studies. This study aimed at investigating the potential effects of...