Validated stability-indicating HPLC-DAD method for determination of the phosphodiesterase (PDE-4) inhibitor roflumilast

A comprehensive stability indicating HPLC with diode array detection method was developed for determination of the recently approved phosphodiesterase type 4 (PDE-4) inhibitor roflumilast (RFL). Effective chromatographic separation was achieved using Durashell C18 column (4.6 × 250 mm, 5 μm particle...

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Bibliographic Details
Main Authors: Tarek S. Belal (Author), Hytham M. Ahmed (Author), Mohamed S. Mahrous (Author), Hoda G. Daabees (Author), Mostafa M. Baker (Author)
Format: Book
Published: Faculty of Pharmacy, Cairo University, 2014-06-01T00:00:00Z.
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