Nanostructured lipid carriers as a novel tool to deliver sclareol: physicochemical characterisation and evaluation in human cancer cell lines

• Principais autores: Gabriel Silva Marques Borges (Autor), Pedro Henrique Dias Moura Prazeres (Autor), Ângelo Malachias de Souza (Autor), Maria Irene Yoshida (Autor), José Mario Carneiro Vilela (Autor), Aline Teixeira Maciel e Silva (Autor), Mariana Silva Oliveira (Autor), Dawidson Assis Gomes (Autor), Margareth Spangler Andrade (Autor), Elaine Maria de Souza-Fagundes (Autor), Lucas Antônio Miranda Ferreira (Autor)
• Formato: Livro
• Publicado em: Universidade de São Paulo, 2021-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Sclareol (SC) is arousing great interest due to its cytostatic and cytotoxic activities in several cancer cell lines. However, its hydrophobicity is a limiting factor for its in vivo administration. One way to solve this problem is through nanoencapsulation. Therefore, solid lipid nanoparticles (SLN...