Effect of antipsychotics on breast tumors by analysis of the Japanese Adverse Drug Event Report database and cell-based experiments

• Hlavní autoři: Tae Maeshima (Autor), Ryosuke Iijima (Autor), Machiko Watanabe (Autor), Satoru Yui (Autor), Fumio Itagaki (Autor)
• Médium: Kniha
• Vydáno: BMC, 2021-04-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Background Since antipsychotics induce hyperprolactinemia via the dopamine D2 receptor, long-term administration may be a risk factor for developing breast tumors, including breast cancer. On the other hand, some antipsychotic drugs have been reported to suppress the growth of breast cancer...