Modified Xiaoyaosan (MXYS) Exerts Anti-depressive Effects by Rectifying the Brain Blood Oxygen Level-Dependent fMRI Signals and Improving Hippocampal Neurogenesis in Mice

• Main Authors: Lei Gao (Author), Peng Huang (Author), Zhaoyang Dong (Author), Tingting Gao (Author), Shaohui Huang (Author), Chuying Zhou (Author), Yuling Lai (Author), Guanghui Deng (Author), Bin Liu (Author), Ge Wen (Author), Zhiping Lv (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As the traditional Chinese herbal formula, Xiaoyaosan and its modified formula have been described in many previous studies with definite anti-depressive effects, but its underlying mechanism remains mystery. Previous work in our lab has demonstrated that depression induced by chronic stress could g...