PARP Inhibition by Flavonoids Induced Selective Cell Killing to BRCA2-Deficient Cells
High consumption of dietary flavonoids might contribute to a reduction of cancer risks. Quercetin and its glycosides have PARP inhibitory effects and can induce selective cytotoxicity in BRCA2-deficient cells by synthetic lethality. We hypothesized that common flavonoids in diet naringenin, hesperet...
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Format: | Book |
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MDPI AG,
2017-10-01T00:00:00Z.
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A1234.567 |
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