PARP Inhibition by Flavonoids Induced Selective Cell Killing to BRCA2-Deficient Cells

High consumption of dietary flavonoids might contribute to a reduction of cancer risks. Quercetin and its glycosides have PARP inhibitory effects and can induce selective cytotoxicity in BRCA2-deficient cells by synthetic lethality. We hypothesized that common flavonoids in diet naringenin, hesperet...

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Main Authors: Cathy Su (Author), Alexis H. Haskins (Author), Chisato Omata (Author), Yasushi Aizawa (Author), Takamitsu A. Kato (Author)
Format: Book
Published: MDPI AG, 2017-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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