The gut-brain axis mediates bacterial driven modulation of reward signaling

• Main Authors: Jiyoung S. Kim (Author), Kevin C. Williams (Author), Rebecca A. Kirkland (Author), Ruth Schade (Author), Kimberly G. Freeman (Author), Carolina R. Cawthon (Author), Allison W. Rautmann (Author), Jessica M. Smith (Author), Gaylen L. Edwards (Author), Travis C. Glenn (Author), Philip V. Holmes (Author), Guillaume de Lartigue (Author), Claire B. de La Serre (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Our goal is to investigate if microbiota composition modulates reward signaling and assess the role of the vagus in mediating microbiota to brain communication. Methods: Male germ-free Fisher rats were colonized with gastrointestinal contents from chow (low fat (LF) ConvLF) or HF (ConvHF)...