Evaluation of the potential impact on pharmacokinetics of various cytochrome P450 substrates of increasing IL‐6 levels following administration of the T‐cell bispecific engager glofitamab

Abstract Glofitamab is a novel T cell bispecific antibody developed for treatment of relapsed‐refractory diffuse large B cell lymphoma and other non‐Hodgkin's lymphoma indications. By simultaneously binding human CD20‐expressing tumor cells and CD3 on T cells, glofitamab induces tumor cell lysi...

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Main Authors: Nassim Djebli (Author), Neil Parrott (Author), Felix Jaminion (Author), Amaury O'Jeanson (Author), Elena Guerini (Author), David Carlile (Author)
Format: Book
Published: Wiley, 2024-03-01T00:00:00Z.
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Call Number: A1234.567
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