Evaluation of the potential impact on pharmacokinetics of various cytochrome P450 substrates of increasing IL‐6 levels following administration of the T‐cell bispecific engager glofitamab

Abstract Glofitamab is a novel T cell bispecific antibody developed for treatment of relapsed‐refractory diffuse large B cell lymphoma and other non‐Hodgkin's lymphoma indications. By simultaneously binding human CD20‐expressing tumor cells and CD3 on T cells, glofitamab induces tumor cell lysi...

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Hoofdauteurs: Nassim Djebli (Auteur), Neil Parrott (Auteur), Felix Jaminion (Auteur), Amaury O'Jeanson (Auteur), Elena Guerini (Auteur), David Carlile (Auteur)
Formaat: Boek
Gepubliceerd in: Wiley, 2024-03-01T00:00:00Z.
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