Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection

• Asıl Yazarlar: Luis Fernando Delgadillo-Silva (Yazar), Anastasia Tsakmaki (Yazar), Nadeem Akhtar (Yazar), Zara J. Franklin (Yazar), Judith Konantz (Yazar), Gavin A. Bewick (Yazar), Nikolay Ninov (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Islet inflammation and cytokine production are implicated in pancreatic β-cell dysfunction and diabetes pathogenesis. However, we lack therapeutics to protect the insulin-producing β-cells from inflammatory damage. Closing this clinical gap requires the establishment of new disease models of islet i...