Non-Cryoprecipitation Separation of Coagulation FVIII and Prothrombin Complex Proteins by Pseudoaffinity Calcium Elution Chromatography Using Anion Exchange Resin

Non-Cryoprecipitation Separation of Coagulation FVIII and Prothrombin Complex Proteins by Pseudoaffinity Calcium Elution Chromatography Using Anion Exchange Resin

Hemophilia A is treated with human plasma coagulation factor VIII (FVIII) replacement therapy and Hemophilia B with coagulation factor IX, which is purified from prothrombin complex concentrate (PCC). In this paper we evaluated the separation of FVIII and PCC by directly loading raw thawed plasma to...

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Main Authors: Gabriel Pinna Feliciano (Author), Sara Hayama Arimori (Author), Vinicius Watanabe Nakao (Author), Joice Rodrigues Dos Santos (Author), Elizabeth A. L. Martins (Author), Marcelo Porto Bemquerer (Author), Elisabeth Cheng (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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