Case Report: Bosentan and Sildenafil Exposure in Human Milk - A Contribution From the ConcePTION Project

• Main Authors: Nina Nauwelaerts (Author), Michael Ceulemans (Author), Neel Deferm (Author), An Eerdekens (Author), Bart Lammens (Author), Yeghig Armoudjian (Author), Kristel Van Calsteren (Author), Karel Allegaert (Author), Loes de Vries (Author), Pieter Annaert (Author), Anne Smits (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Quantitative information on disposition of maternal medicines in human milk remains a major knowledge gap. This case report presents the clinical and pharmacokinetic data of a single mother-infant pair exposed to bosentan and sildenafil for the treatment of pulmonary arterial hypertens...