Pharmaceutical and Safety Profile Evaluation of Novel Selenocompounds with Noteworthy Anticancer Activity

• Main Authors: Małgorzata Anna Marć (Author), Enrique Domínguez-Álvarez (Author), Gniewomir Latacz (Author), Agata Doroz-Płonka (Author), Carmen Sanmartín (Author), Gabriella Spengler (Author), Jadwiga Handzlik (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prior studies have reported the potent and selective cytotoxic, pro-apoptotic, and chemopreventive activities of a cyclic selenoanhydride and of a series of selenoesters. Some of these selenium derivatives demonstrated multidrug resistance (MDR)-reversing activity in different resistant cancer cell...