Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release

• मुख्य लेखकों: Ni Dong (लेखक), Chune Zhu (लेखक), Junhuang Jiang (लेखक), Di Huang (लेखक), Xing Li (लेखक), Guilan Quan (लेखक), Yang Liu (लेखक), Wen Tan (लेखक), Xin Pan (लेखक), Chuanbin Wu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

This study aimed to prepare poly (D, L-lactic-co-glycolic acid) microspheres (PLGA-Ms) by a modified solid-in-oil-in-water (S/O/W) multi-emulsion technique in order to achieve sustained release with reduced initial burst and maintain efficient drug concentration for a prolonged period of time. Compo...