A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12

• Main Authors: Alexa Burger (Author), Aleksandr Vasilyev (Author), Ritu Tomar (Author), Martin K. Selig (Author), G. Petur Nielsen (Author), Randall T. Peterson (Author), Iain A. Drummond (Author), Daniel A. Haber (Author)
• Format: Book
• Published: The Company of Biologists, 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither chemotherapeutic nor targeted therapeutic approaches h...