The Effectiveness of Dichloroacetate on Human Glioblastoma Xenograft Growth Depends on Na+ and Mg2+ Cations

• Main Authors: Donatas Stakišaitis (Author), Eligija Damanskienė (Author), Rūta Curkūnavičiūtė (Author), Milda Juknevičienė (Author), Marta Maria Alonso (Author), Angelija Valančiūtė (Author), Saulius Ročka (Author), Ingrida Balnytė (Author)
• Format: Book
• Published: SAGE Publishing, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study's aim was to investigate the effectiveness of sodium dichloroacetate (NaDCA) or magnesium dichloroacetate (MgDCA) on adult U87 MG and pediatric PBT24 cell lines glioblastoma (GB) xenografts in a chicken chorioallantoic membrane (CAM) model. The study groups were: treated with 10 mM, 5...