Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome
SUMMARY Mutations in the imprinted CDKN1C gene are associated with the childhood developmental disorder Beckwith-Wiedemann syndrome (BWS). Multiple mouse models with deficiency of Cdkn1c recapitulate some aspects of BWS but do not exhibit overgrowth of the newborn, a cardinal feature of patients wit...
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The Company of Biologists,
2011-11-01T00:00:00Z.
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