Effects of estradiol on HIF-1α expression and trophoblast differentiation in first trimester villous explant cultures

• Main Authors: Geum Joon Cho (Author), Lyn Hwa Lee (Author), Bona Lee (Author), Jaeeun Lee (Author), Ki-Hoon Ahn (Author), Soon-Cheol Hong (Author), Hai-Joong Kim (Author), Min-Jeong Oh (Author)
• Format: Book
• Published: Korean Society of Obstetrics and Gynecology, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveThe purpose of this study was to investigate the effects of estradiol on the expression of hypoxia-inducible factor (HIF)-1α and the differentiation of trophoblasts in human first trimester villous explant cultures.MethodsVillous explant cultures were established from first trimester human...