T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives

• Main Authors: Alessia Alunno (Author), Francesco Carubbi (Author), Onelia Bistoni (Author), Sara Caterbi (Author), Elena Bartoloni (Author), Giulia Mirabelli (Author), Francesca Cannarile (Author), Paola Cipriani (Author), Roberto Giacomelli (Author), Roberto Gerli (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Historically, primary Sjögren's syndrome (pSS) was thought to be a T helper (h) 1 driven disease due to the predominance of CD4+T lymphocytes and their products in target organs and peripheral blood of patients. In the last decades, the identification of a number of T cell subsets, including T...