Synthesis, Molecular Docking, and Bioactivity Study of Novel Hybrid Benzimidazole Urea Derivatives: A Promising α-Amylase and α-Glucosidase Inhibitor Candidate with Antioxidant Activity

• Main Authors: Lotfi M. Aroua (Author), Abdulelah H. Alosaimi (Author), Fahad M. Alminderej (Author), Sabri Messaoudi (Author), Hamdoon A. Mohammed (Author), Suliman A. Almahmoud (Author), Sridevi Chigurupati (Author), Abuzar E. A. E. Albadri (Author), Nejib H. Mekni (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel series of benzimidazole ureas <b>3a-h</b> were elaborated using 2-(1<i>H</i>-benzoimidazol-2-yl) aniline <b>1</b> and the appropriate isocyanates <b>2a-h</b>. The antioxidant and possible antidiabetic activities of the target benzimidazole-urea...