Ocular immune responses, Chlamydia trachomatis infection and clinical signs of trachoma before and after azithromycin mass drug administration in a treatment naïve trachoma-endemic Tanzanian community.

• Main Authors: Athumani M Ramadhani (Author), Tamsyn Derrick (Author), David Macleod (Author), Patrick Massae (Author), Aiweda Malisa (Author), Kelvin Mbuya (Author), Tara Mtuy (Author), William Makupa (Author), Chrissy H Roberts (Author), Robin L Bailey (Author), David C W Mabey (Author), Martin J Holland (Author), Matthew J Burton (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Trachoma, caused by Chlamydia trachomatis, remains the leading infectious cause of blindness worldwide. Persistence and progression of the resulting clinical disease appears to be an immunologically mediated process. Azithromycin, which is distributed at the community...