Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi‐Ethnic Allele and Copy Number Variant Detection

• Main Authors: Stuart A. Scott (Author), Erick R. Scott (Author), Yoshinori Seki (Author), Annette J. Chen (Author), Richard Wallsten (Author), Aniwaa Owusu Obeng (Author), Mariana R. Botton (Author), Neal Cody (Author), Huanzhi Shi (Author), Geping Zhao (Author), Paul Brake (Author), Paola Nicoletti (Author), Yao Yang (Author), Maria Delio (Author), Lisong Shi (Author), Ruth Kornreich (Author), Eric E. Schadt (Author), Lisa Edelmann (Author)
• Format: Book
• Published: Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To develop a novel pharmacogenetic genotyping panel, a multidisciplinary team evaluated available evidence and selected 29 genes implicated in interindividual drug response variability, including 130 sequence variants and additional copy number variants (CNVs). Of the 29 genes, 11 had guidelines pub...