Bivalirudin Attenuates Thrombin-Induced Endothelial Hyperpermeability via S1P/S1PR2 Category: Original Articles

Aims: To explore the role of the Sphingosine 1-Phosphate (S1P)/Receptor2 (S1PR2) pathway in thrombin-induced hyperpermeability (TIP) and to test whether bivalirudin can reverse TIP via the S1P-S1PRs pathway.Methods and Results: Using western blot, we demonstrated that Human umbilical vein endothelia...

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Main Authors: Haowen Ye (Author), Yizhi Zhang (Author), Yihui Huang (Author), Biao Li (Author), Ruhao Cao (Author), Libing Dai (Author), Bin Huang (Author), Pingge Tian (Author), Li Li (Author), Yaling Han (Author)
Format: Book
Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
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