Bivalirudin Attenuates Thrombin-Induced Endothelial Hyperpermeability via S1P/S1PR2 Category: Original Articles

• Prif Awduron: Haowen Ye (Awdur), Yizhi Zhang (Awdur), Yihui Huang (Awdur), Biao Li (Awdur), Ruhao Cao (Awdur), Libing Dai (Awdur), Bin Huang (Awdur), Pingge Tian (Awdur), Li Li (Awdur), Yaling Han (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Aims: To explore the role of the Sphingosine 1-Phosphate (S1P)/Receptor2 (S1PR2) pathway in thrombin-induced hyperpermeability (TIP) and to test whether bivalirudin can reverse TIP via the S1P-S1PRs pathway.Methods and Results: Using western blot, we demonstrated that Human umbilical vein endothelia...