Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Background: Blood-cerebrospinal fluid (CSF) barrier transporters affect the influx and efflux of drugs. The antiretrovirals tenofovir and emtricitabine may be substrates of blood-brain barrier (BBB) and blood-CSF barrier transporters, but data are limited regarding the pharmacogenetics and pharmacok...

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Main Authors: Eric H. Decloedt (Author), Phumla Z. Sinxadi (Author), Lubbe Wiesner (Author), John A. Joska (Author), David W. Haas (Author), Gary Maartens (Author)
Format: Book
Published: AOSIS, 2021-04-01T00:00:00Z.
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