TNFα-Induced Necroptosis and Autophagy via Supression of the p38-NF-κB Survival Pathway in L929 Cells

Abstract.: Tumor necrosis factor alpha (TNFα) has been reported to induce necroptosis and autophagy, but its mechanisms remain unclear. In this study, we found that TNFα significantly induced necroptosis and autophagy in murine fibrosarcoma L929 cells. The necroptosis inhibitor necrostatin-1 (Nec-1)...

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Main Authors: Yuan-Chao Ye (Author), Lu Yu (Author), Hong-Ju Wang (Author), Shin-ichi Tashiro (Author), Satoshi Onodera (Author), Takashi Ikejima (Author)
Format: Book
Published: Elsevier, 2011-01-01T00:00:00Z.
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